L-5-hydroxytryptophan (a.k.a. 5-HTP) is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitters, serotonin and melatonin, from tryptophan. Serotonin is an important neurotransmitter involved in the regulation of endocrine and brain activity responsible for emotion, appetite, and sleep/wake cycles.
Serotonin is a neurotransmitter found primarily in the gastrointestinal tract, platelets and central nervous system. Almost 90% of the human body’s total serotonin is located in the alimentary canal, where it is used to regulate peristalsis. In the central nervous system, neurons use serotonin to regulate various functions including mood, appetite, and sleep. In humans, serotonin levels are affected by diet, specifically carbohydrate intake and the amino acid, tryptophan. Increased intake of tryptophan or its metabolic intermediate, 5-HTP, may increase serotonin levels and help support healthy mood and appetite as well as sleep through its role in serotonin synthesis. PV 5-HTP extract is made under strict European quality standards, which are comparable to Over-The-Counter drug standards in the US. It provides optimal levels of naturally occurring L-5-hydroxytryptophan. Our formula is synergized with important nutrients like vitamin C and B-6, which aid the conversion of tryptophan to serotonin in the body.